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HyaluGuard is a cosmetic ingredient for anti-skin-sagging products of completely natural origin that focuses on hyaluronic acid existing in the dermis.
April 15, 2025
By: Lianna Albrizio
Ichimaru Pharcos Co., Ltd.’s natural ingredient, HyaluGuard, has been honored with the BSB Innovation Award for natural products/raw materials in the “active” cateogory.
HyaluGuard (INCI: Artemisia Capillaris Flower Extract) is a cosmetic ingredient for anti-skin-sagging products of completely natural origin that focuses on hyaluronic acid (HA) existing in the dermis. HA in the epidermis was known to be degraded by HYAL1/2. However, HA in the dermis, which contributes to stable skin structure, was recently revealed to be degraded by HYBID. HyaluGuard prevents the expression of HYBID via up-regulation of micro-RNA. As a result, HyaluGuard prevents skin sagging by acting as a guardian of hyaluronic acid.
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